Give to Save the Children International, which works in around 120 countries delivering lifesaving aid, protection and education to children caught in poverty, conflict and disaster. The organisation runs both emergency response and longer-term development programmes side by side.
Similar in scope to the UNICEF gift above, but worth comparing if you want a second broad option, or prefer Save the Children's specific mix of protection, education and disaster response across roughly 120 countries. Running emergency response and longer-term development side by side also means a single gift here can support both an immediate crisis and the slower work of rebuilding afterward.