Islamic Relief Worldwide, founded in 1984 and headquartered in Birmingham, is an international NGO operating in more than 40 countries, providing humanitarian and development aid. It reached 13.1 million people in 2025, and for every £1 donated, 90p is spent directly on helping people in need. The organisation works regardless of race, religion or gender, though it is run according to Islamic values.
With 90p of every £1 spent directly helping people in need, and four decades of operating across 40+ countries, this is a well-established option if a faith-rooted humanitarian organisation is what you're looking for. Worth knowing that aid is given regardless of the recipient's own religion, even though the organisation itself is run according to Islamic values.